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Health Authorities Know What’s Potentially Causing Vaping-Related Deaths

Topline: The CDC announced on Thursday that vitamin E acetate, a chemical found in skincare products that is dangerous when heated or inhaled, is a “very strong culprit” in the spate of vaping-related lung injuries and deaths have for months perplexed and alarmed federal health officials.

  • The CDC determination comes from a study that examined 29 samples from patients with vaping-related lung illnesses. All 29 of them contained traces of vitamin E acetate.
  • No other potential toxins were detected.
  • Vitamin E acetate is a chemical commonly found in skincare products, and it isn’t dangerous when applied to the skin or swallowed. But when heated and inhaled through vaping devices, the chemical can cause harm to a patient’s lungs.
  • Vitamin E acetate has been recently used in black market products containing THC, the psychoactive chemical in cannabis, as a thickening agent.
  • But officials do not yet know exactly where the vitamin E acetate is coming from.
  • THC was found in 23 of 28 patients, including three who said they had not used THC products, while nicotine was detected in 16 of 26 patients.
  • Officials cautioned that there could more than one toxin causing the illnesses, and more evidence is needed to establish a causal link between vitamin E acetate and the injuries.

Crucial quote: “These findings provide direct evidence of vitamin E acetate at the primary site of injury within the lungs,” said Anne Schuchat, principal deputy director at the CDC, in a press call Thursday. “And the samples reflect patients from across the country.”

Key background: As of Tuesday 2,051 cases of vaping-related illnesses have been reported along with 39 deaths, according to the CDC. The cause of the lung injuries and deaths have prompted health officials to warn against vaping altogether and for state and federal lawmakers to mull or impose vaping sale bans.

Further reading: Read the CDC’s report on the study here.

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I’m a San Francisco-based reporter covering breaking news at Forbes. Previously, I’ve reported for USA Today, Business Insider, The San Francisco Business Times and San Jose Inside. I studied journalism at Syracuse University’s S.I. Newhouse School of Public Communications and was an editor at The Daily Orange, the university’s independent student newspaper. Follow me on Twitter @rachsandl or shoot me an email rsandler@forbes.com.

Source: Health Authorities Know What’s Potentially Causing Vaping-Related Deaths

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Vaping & E-Cigarette related illnesses & deaths have gathered significant media attention. Join Dr. Seheult of https://www.MedCram.com as he illustrates key points about vaping and E cigarette-related acute pulmonary illness & disease symptoms, diagnosis, CXR, and CT scan findings that we understand at this time. More information and studies are needed as vaping deaths and hospitalizations in 2019 continue to rise (some are calling it a “vaping epidemic”). See the second video in this series on the treatment of vaping associated pulmonary injury: https://youtu.be/7TO7Cfi_o38 Links to articles from the New England Journal of Medicine referenced in this video: Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin — Preliminary Report: https://www.nejm.org/doi/full/10.1056… Vaping-Induced Lung Injury: https://www.nejm.org/doi/full/10.1056… Instructor: Roger Seheult, MD Co-Founder of MedCram.com Clinical and Exam Preparation Instructor Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine. Visit https://www.MedCram.com for top-rated medical videos, over 30 hours of category 1 CME and CE, and over 100 free lectures. MedCram: Medical education topics explained clearly including: Respiratory lectures such as Asthma, COPD, and vape / E cigarette related lung disease. Renal lectures on Acute Renal Failure and Adrenal Gland. Internal medicine videos on Oxygen Hemoglobin Dissociation Curve and Medical Acid Base. A growing library on critical care topics such as Shock, Diabetic Ketoacidosis (DKA), and Mechanical Ventilation. Cardiology videos on Hypertension, ECG / EKG Interpretation, and heart failure. VQ Mismatch and Hyponatremia lectures have been popular among medical students and physicians. The Pulmonary Function Tests (PFTs) videos and Ventilator-associated pneumonia bundles and lectures have been particularly popular with RTs. NPs and PAs have given great feedback on Pneumonia Treatment and Liver Function Tests among many others. Dr. Jacquet teaches our FAST exam tutorial & bedside ultrasound courses. Many nursing students have found the Asthma and shock lectures very helpful. We’re starting a new course series on clinical ultrasound/ultrasound medical imaging. Recommended Audience – Medical professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review and test prep for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NBDE, RN, RT, MD, DO, PA, NP school and board examinations. More from MedCram.com medical lectures: Blog: https://blog.medcram.com Facebook: https://www.facebook.com/MedCram Google+: https://plus.google.com/u/1/+Medcram Twitter: https://twitter.com/MedCramVideos Subscribe to the official MedCram.com YouTube Channel: https://www.youtube.com/subscription_… Produced by Kyle Allred PA-C Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical education and exam preparation purposes, and not intended to replace recommendations by your doctor or health care provider. #Vaping #ECigarettes #vapingdeaths

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This Inexpensive Action Lowers Hospital Infections And Protects Against Flu Season

Harvard Medical School graduate and lecturer, Stephanie Taylor, is something of an Indiana Jones of medicine. She’s a determined scientist who can’t seem to sit still. Along with a resume full of accolades and publications, she’s a skydiver with 1,200 jumps. She solves haunting medical mysteries. “Anything that seems scary, I say I need to learn more about that,” she explained in a recent interview

While practicing pediatric oncology at a major teaching hospital, Taylor wondered why so many of her young patients came down with infections and the flu, despite the hospital’s herculean efforts at prevention. Her hunch: the design and infrastructure of the building contributed somehow.

Dr. Taylor embarked on a quest to find out if she was right. First, the skydiving doctor made a career jump: She went back to school for a master’s in architecture, and then began research on the impact of the built environment on human health and infection. Ultimately, she found a lost ark.

She and colleagues studied 370 patients in one unit of a hospital to try to isolate the factors associated with patient infections. They tested and retested 8 million data points controlling for every variable they could think of to explain the likelihood of infection. Was it hand hygiene, fragility of the patients, or room cleaning procedures? Taylor thought it might have something to do with the number of visitors to the patient’s room.

While all those factors had modest influence, one factor stood out above them all, and it shocked the research team. The one factor most associated with infection was (drum roll): dry air. At low relative humidity, indoor air was strongly associated with higher infection rates. “When we dry the air out, droplets and skin flakes carrying viruses and bacteria are launched into the air, traveling far and over long periods of time. The microbes that survive this launching tend to be the ones that cause healthcare-associated infections,” said Taylor. “Even worse, in addition to this increased exposure to infectious particles, the dry air also harms our natural immune barriers which protect us from infections.”

Since that study was published, there is now more research in peer-reviewed literature observing a link between dry air and viral infections, such as the flu, colds and measles, as well as many bacterial infections, and the National Institutes of Health (NIH) is funding more research. Taylor finds one of the most interesting studies from a team at the Mayo Clinic, which humidified half of the classrooms in a preschool and left the other half alone over three months during the winter. Influenza-related absenteeism in the humidified classrooms was two-thirds lower than in the standard classrooms—a dramatic difference. Taylor says this study is important because its design included a control group: the half of classrooms without humidity-related intervention.

Scientists attribute the influence of dry air to a new understanding about the behavior of airborne particles, or “infectious aerosol transmissions.” They used to assume the microbes in desiccated droplets were dead, but advances in the past several years changed that thinking. “With new genetic analysis tools, we are finding out that most of the microbes are not dead at all. They are simply dormant while waiting for a source of rehydration,” Taylor explained. “Humans are an ideal source of hydration, since we are basically 60% water. When a tiny infectious particle lands on or in a patient, the pathogen rehydrates and begins the infectious cycle all over again.”

These findings are especially important for hospitals and other health settings, because dry air is also associated with antibiotic resistance, which can devastate whole patient populations. Scientists now believe resistant organisms do not develop only along the Darwinian trajectory, where mutated bacteria produce a new generation of similarly mutated offspring that can survive existing antibiotics. Resistant pathogens in infectious aerosols do not need to wait for the next generation, they can instantly share their resistant genes directly through a process called horizontal gene transfer.

According to her research, and subsequent studies in the medical literature, the “sweet spot” for indoor air is between 40% and 60% relative humidity. An instrument called a hygrometer, available for about $10, will measure it. Every hospital, school, and home should have them, according to Taylor, along with a humidifier to adjust room hydration to the sweet spot.

Operating rooms, Taylor notes, are often kept cooler than other rooms to keep gown-wearing surgical staff comfortable. Cool air holds less water vapor than warm air, so condensation can more easily occur on cold, uninsulated surfaces. Consequently, building managers often turn humidifiers off instead of insulating cold surfaces. This quick fix can result in dry air, and Taylor urges hospitals to bring the operating room’s relative humidity up, even when it is necessary, to maintain a lower temperature. Taylor’s research suggests this reduces surgical site infections.

Taylor travels the country speaking with health care and business groups to urge adoption of the 40%–60% relative humidity standard. And she practices what she preaches. “My husband has ongoing respiratory problems and had at least one serious illness each winter. Ever since we started monitoring our indoor relative humidity and keeping it around 40%, even when using our wood stove, he has not been sick. Our dogs also love it because they do not get static electricity shocks when being petted in the wintertime!”

The bad news is that it takes on average of 17 years for scientific evidence to be put into medical practice, according to a classic study. The good news is that Taylor is on the case, and she’s on a crusade against the destruction of bacteria and viruses. She’s not waiting 17 years. Jock, start the engine.

Follow me on Twitter. Check out my website.

I run an organization called The Leapfrog Group with a membership of highly impatient business leaders fed up with problems with injuries, accidents, and errors in hospitals. I can’t stand the sight of blood but I’ve worked in healthcare over 20 years, including a rural hospital system, Mayor Rudolph Giuliani’s health policy office, and the National League for Nursing. Follow me on twitter: @leahbinder.

Source: This Inexpensive Action Lowers Hospital Infections And Protects Against Flu Season

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The flu season in the U.S. has already claimed a number of lives in what the Centers for Diseases Control and Prevention (CDC) has called one of most severe flu seasons in nearly a decade. “People often forget that tens of thousands of Americans will die each year from influenza infection; the vast majority of those who die are those who have underlying medical comorbidities,” says Dr. Pritish Tosh, an infectious diseases specialist at Mayo Clinic. “They have heart disease or lung disease, and influenza tips them over and they end up dying from their underlying medical comorbidity, or chronic illness.” More health and medical news on the Mayo Clinic News Network http://newsnetwork.mayoclinic.org/

A Low-Fat Diet May Lower the Risk of Dying from Breast Cancer

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Breast cancer treatments have come a long way in recent decades, but understanding how to prevent tumors from forming in the first place has been a major challenge.

In a new study being presented at the annual American Society of Clinical Oncology meeting in Chicago next month, researchers report intriguing evidence that a low-fat diet, similar to the kind doctors recommend for heart health, is also linked to a lower risk of dying from breast cancer.

The study analyzed data from the Women’s Health Initiative, a large trial sponsored by the National Institutes of Health that studies the health effects of hormone therapy, diet and certain supplements on the health of more than 160,000 postmenopausal women. In this trial, researchers led by Dr. Rowan Chlebowski, an investigator at LA Biomedical Research Institute at Harbor-UCLA Medical Center, focused on a group of nearly 49,000 women who were randomly assigned to follow either a low-fat diet or a control diet for 8.5 years. The low-fat diet group aimed to reduce their fat intake to 20% of their total daily calories and to increase the consumption of fruit, vegetables and grains. None of the women had breast cancer at the start of the study.

After the study ended, the rates of new breast cancers were about the same in the two groups, but women who were diagnosed with breast cancer in the interim had a 35% lower risk of dying from any cause compared to those on the control diet. Even 20 years after the study ended, the women who ate the low-fat diet continued to have a 15% lower mortality risk. And in the longer follow-up data, their risk of dying specifically from breast cancer was 21% lower than that of the women who didn’t change their diet.

“This is a very exciting result for us,” says Chlebowski. “Now we have randomized clinical trial evidence that dietary moderation, which is achievable by many, can have health benefits including reducing risk of death from breast cancer. That’s pretty good; it’s hard not to be happy about that.”

The study is the first to rigorously test a potential factor that could influence deaths from breast cancer. Earlier observational studies did not assign volunteers to specific diets but looked at cancer outcomes depending on what people, on their own, chose to eat. In this study, volunteers were provided with dietary guidelines to follow about what to eat. “Until this study, we lacked any data from a prospective randomized control trial, which is the gold standard, for showing that a dietary approach really does reduce the risk of dying from breast cancer,” says Dr. Neil Iyengar, a medical oncologist at Memorial Sloan Kettering Cancer Center, who was not involved in the study. “Many of us who are proponents of considering diet and exercise in the cancer treatment plan are excited by this trial data because it is the first to show in a very robust way that we can improve outcomes and prevent cancer-related deaths just by changing the diet.”

In a separate sub-study, the research team also showed that the longer women were on the modified diet, the lower their risk of death during the study period. The results should give doctors more confidence in considering diet when discussing treatment options with women who are diagnosed with breast cancer. While the study did not find a significant connection between dietary changes and the incidence of new breast cancer, the results do suggest that modifying the diet can lower a woman’s risk of dying from any cause, or from breast cancer, if she is diagnosed with the disease.

The reason for that, says Iyengar, may have to do with the diet’s “dose.” It’s possible, for example, that the effect of the dietary change is greater on tiny tumors in the breast tissue that are already established, although they aren’t robust enough yet to lead to a diagnosis of breast cancer. “The effect of this diet may be stronger in preventing the growth of already established tumors rather than preventing the development of tumors,” he says. “What this trial does is position us to take a deeper dive, now that we know we can effectively change the tumor or cancer behavior with diet.”

Chlebowski plans to dig deeper into the data to find out more about how diet is working to lower deaths from breast cancer. During the trial, women provided blood samples both at the start of the study and one year later, so he and his team may find factors that changed among the women on the diet compared to those on the control plan.

In the meantime, he hopes cancer doctors will talk about diet with their patients who might be at higher risk of developing breast cancer. Though not all women in the study were able to lower their fat intake to 20% of their daily calories,“these dietary changes are achievable by many,” he says. Even though not all of the women on the low-fat diet met the target, the study showed that the modifications still reduced risk of dying from any cause and from breast cancer. “It’s about taking smaller pieces of meat, and adding vegetables to the plate to balance things out,” he says.

By Alice Park

Source: https://time.com/

 

Sugar and anxiety are connected in surprising ways

 

There are some things you know are going to make your anxiety worse: WebMDing your stomach ache, foregoing sleep to list all the ways your work presentation could go wrong, calling your friend who freaks out about everything…But treating yourself to a scoop of Rocky Road or a cupcake from your favorite bakery, that’s going to make you feel better right?

Sometimes, 100 percent yes. But other times, that sweet treat can backfire, sneakily causing all sorts of changes that can lead to the opposite of feeling good: anxiety. Here, health experts break down the relationship between sugar and anxiety, and what you can do to combat it.

How are sugar and anxiety related?

The problem with sugar, says hormone health educator Candace Burch, is that it causes blood sugar spikes and drops, which directly affects mood. “The rush of sugar leads to sugar highs, giving a lot of energy, but then the lows lead to feeling sluggish and down.”

“Sugar can exacerbate your feelings of anxiety because of the way our bodies respond to digesting them,” adds Brigitte Zeitlin, RD, owner of BZ Nutrition, a New York-based nutrition practice. “[Sugary foods] cause your blood sugar to spike and then drop faster than they would after eating non-high-sugar-foods. This quick spike and drop causes you to feel uneasy and can even at times mimic a panic attack.” Having low blood sugar levels can actually put the body into a stress response, which, as Zeitlin mentions, can increase anxiety.

Our bodies obviously don’t like being stressed or anxious, says Zeitlin. People combat that in various ways, including reaching for sugary foods. “Foods high in sugar trigger the release of serotonin, which is a feel good hormone,” Zeitlin says. “We are trained to eat sugar and feel good, which makes it understandable why people stress eat, because they just want to feel better when they are feeling stressed and anxious.”

However, when your body is stressed or anxious, you also have higher levels of cortisol (a.k.a. the “stress hormone”). Zeitlin says when this happens, your body suppresses the release of insulin, the hormone that takes up glucose to use for energy. You now have a one-two punch of spiked blood sugar levels (since you’re eating more sugar to combat your stress) and storing excess sugar as fat since you’re not turning it into energy. “So, eating more sugar when you are stressed or anxious just amplifies the amount of sugar your body would naturally have already flowing, and contributes to more severe drops in blood sugar and more drastic drops in your mood,” she says. Enter a cycle of turning to something sweet every time they need another energy and mood boost, and a subsequent rollercoaster of ups and downs which can also contribute to feelings of anxiety.

This sugar-and-anxiety cycle isn’t just relegated to the daytime hours. “High-sugar foods can keep you up because of their energy that prevents your natural stress-booster of sleep from kicking in,” Zeitlin says. “When we don’t get enough sleep we feel even more anxious and stressed because our body missed an opportunity to process it properly.” You’re now going into the next day with less sleep, and thus lower energy levels and higher stress levels. And what do many people reach for to combat stress and anxiety? You guessed it: sugar.

And “high-sugar foods” doesn’t just mean candy, cookies, and cake. “Studies have found that women who eat more refined carbohydrates (baked goods, candy, white breads/rice/cereals, bagels, etc) were more likely to suffer from depression and mood swings because of the drastic peaks and deeps in blood sugar levels,” Zeitlin says.

How to keep sugar from contributing to anxiety

Of course, this isn’t just to freak you out and make you throw out all of the dairy-free ice cream in the fridge. Lots of other things can contribute to anxiety, including stress, coffee, work, and even family relationships—so cutting out Oreos isn’t the magic bullet for reducing anxiety. But the impact of sugar on anxiety levels can affect anyone, says Zeitlin—and if you have an existing anxiety disorder, sugary foods will likely exacerbate your condition, she adds.

One way to combat this is certainly to reduce your sugar intake, including processed foods and breads. It’s also a good idea to load up on foods low in sugar and high in fiber (think veggies, fruit like berries, and whole grains)—Zeitlin says they have a much more even effect on your blood sugar, which can help cut back on feelings of “increased anxiety.” She also recommends stopping eating about two hours before you go to sleep. “This gives your body time to properly digest and process the food—sugary or not—and let that energy subside in time for you to actually fall asleep and stay asleep.”

When you are eating foods higher in sugar, Burch suggests pairing it with foods higher in fiber and healthy fats. “This slows the absorption of sugar, preventing it from spiking blood sugar as much,” she says, and thus making it less likely to put you in an anxiety spiral.

But all this comes with a big caveat: Changing one’s diet shouldn’t be the only thing a person does to fight back against anxiety. “Changing your diet to limit high-sugar foods will not treat or cure your anxiety disorder, but it will help manage it better and optimize the times you are feeling good and less anxious,” says Zeitlin. Psychologist Gail Saltz, PhD, says some ways to reduce anxiety not related to food include deep breathing, working out, and (to bring it all full circle) getting enough sleep. If none of these lifestyle changes are helping, it’s essential to see a professional to help you come up with a treatment plan.

“Sugary foods contribute to mood swings and anxiety. Period,” Zeitlin says. And now that you understand the connection, it’ll be easier to be more mindful when you are consuming foods with sugar in them.

Additional reporting by Jessie Van Amburg.

If you want to cut out sugar completely but don’t know how, here’s some tips. And if your anxiety is worst in the morning, this could be why.

By: Emily Laurence

 

Source: Sugar and anxiety are connected in surprising ways | Well+Good

Vitamins, Minerals and Supplements: how to Naturally Boost your Health (and more!)

Vitamins and Minerals (also known as Micronutrients)are important substances that allow your body to function and stay healthy. If you already have a balanced diet, you probably do not need to take them as supplements, and yet in some cases people should. This article is the result of a collaboration with Annalisa Brigo, a Nutrition […]

via Vitamins, Minerals and Supplements: how to Naturally Boost your Health (and more!) [Collaboration Post]. — THE PHYSIO FORMULA

What Happens When You Drink a Gallon of Water a Day?

I am that person who hates drinking water. Where others enjoy a satisfying thirst quencher, I suffer through a barrage of sulfur, algae, swimming pool, and old metal pipes. Most days I avoid the issue entirely, subsisting on coffee, herbal tea, and the occasional LaCroix. But a few months ago, I began to suspect that chronic dehydration was the reason I continually felt tired and achy. So, in an effort to overcompensate my way to better life habits, I decided to slosh through a feat known across the internet as the Water Gallon Challenge…..

Source: What Happens When You Drink a Gallon of Water a Day?

Iron deficiency: 6 Signs You’re Low In Iron

Low iron is the most common and widespread nutritional disorder in the world, and is the only nutrient deficiency that is significantly prevalent in the western world, according to the World Health Organization. A staggering 2 billion people (that’s over 30 per cent of the world’s population) are thought to suffer from some degree of iron deficiency. And it’s especially common in women, specifically those of childbearing age. So chances are, you’re low in it too………

Source: 6 signs you’re low in iron

Top Surgeon : How To Proporly Wash Out Your Bowels – Gundry MD

Millions of Americans suffer from low energy, digestive discomfort, and trouble losing weight. Many also experience achy muscles and joints, skin problems, headaches, and even frequent colds. “If you’re experiencing any of these health issues, the real problem may be Leaky Gut,” says Dr. Steven Gundry. According to Dr. Gundry — who has studied leaky gut for over 20 years — certain foods can cause tears in our gut lining. This, in turn, allows toxins to enter our body that lead to digestive discomfort, food cravings, fatigue, weight gain, and even more health issues…..

Source: https://thenewgutfix.com/leaky-gut-fix_181102A.php?n=rev

The Illegal Ingredients in Your Dietary Supplements – Sumathi Reddy

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Consumers are taking dietary supplements with illegal—and potentially harmful ingredients, a growing body of evidence shows. A new study published online in JAMA Internal Medicine this week found experimental stimulants in dietary supplements both before and after the U.S. Food and Drug Administration issued public warnings about the stimulants. The stimulants aren’t approved for human use and are believed to increase blood pressure and heart rates potentially, says Pieter Cohen, an associate professor at Harvard Medical School and general internist at Cambridge Health Alliance…………..

Read more: https://www.wsj.com/articles/the-illegal-ingredients-in-your-dietary-supplements-1540220500

 

 

 

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The Highs & Lows of Testosterone – Randi Hutter Epstein

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Getting a high testosterone reading offers bragging rights for some men of a certain age and may explain in part the lure of testosterone supplements. But once you are within a normal range, does your level of testosterone, the male hormone touted to build energy, libido and confidence, really tell you that much? Probably not, experts say. Normal testosterone levels in men range from about 300 to 1,000 nanograms per deciliter of blood. Going from one number within the normal zone to another one may not pack much of a punch.

Read more: https://www.nytimes.com/2018/03/27/well/live/testosterone-supplements-low-t-treatment-libido.html

 

 

 

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