caracterdesign | Getty
The average human brain shrinks by approximately 5% per decade after the age of 40. This can have a major impact on memory and focus. What’s more, brain disorders are on the rise. In 2020, 54 million people worldwide had Alzheimer’s disease or other dementias, and that number is expected to grow.
But serious mental decline doesn’t have to be an inevitable part of aging. In fact, certain lifestyle factors have a greater impact than your genes do on whether you’ll develop memory-related diseases. As a neuroscience researcher, here are seven hard rules I live by to keep my brain sharp and fight off dementia.
1. Keep blood pressure and cholesterol levels in check
Your heart beats roughly 115,000 times a day, and with every beat, it sends about 20% of the oxygen in your body to your brain. High blood pressure can weaken your heart muscle, and is one of the leading causes of strokes. Ideally, your blood pressure should be no higher than 120/80.
Cholesterol is critical to your brain and nervous system health, too. The American Heart Association recommends getting your cholesterol levels measured every four to six years.
2. Manage sugar levels
Blood sugar is the primary fuel of the brain. Not enough of it, and you have no energy; too much, and you can destroy blood vessels and tissue, leading to premature aging and cardiovascular disease.
Keep in mind that sugar isn’t enemy, excess sugar is. It’s easy for grams of sugar to add up, even if you think you’re being careful — and usually, sugar will sneak in through packaged foods.
Where is the sugar hidden? Look for these in the ingredients list:
- Dextrose
- Fructose
- Galactose
- Glucose
- Lactose
- Maltose
- Sucrose
And be wary of any product that includes syrup, such as agave nectar syrup or high-fructose corn syrup.
3. Get quality sleep
Studies show that people with untreated sleep apnea raise their risk of memory loss by an average of 10 years before the general population. For most people, a healthy brain needs somewhere between seven and nine hours of sleep a night.
My tips for memory-boosting, immune-enhancing sleep:
- Keep a consistent bedtime and wake-up schedule.
- Turn off devices one hour before bedtime.
- Do something relaxing before bedtime, like listening to soft music or doing mindful breathing exercises.
- Go outside and get in natural sunlight as soon as you can after waking up.
4. Eat a nutritious diet
One way I keep things simple is to have most, if not all, of these items in my grocery cart:
- Fatty fish like salmon
- Avocados
- Nuts
- Blueberries
- Cruciferous veggies like arugula, broccoli, Brussels sprouts and collard greens
When food shopping, I ask myself three questions to help determine whether something is good for my brain:
1. Will it spoil? In many cases, perishable is a good thing. The additives and preservatives that keep food from spoiling wreak havoc on your gut bacteria.
2. Are there tons of ingredients in that packaged food? And for that matter, can you pronounce the ingredients? Or does it look like the makings of a chemical experiment? Also avoid anything where sugar is one of the first few ingredients.
3. Do you see a rainbow on your plate? The chemicals that give fruits and vegetables their vibrant colors help boost brain health.
5. Don’t smoke (and avoid secondhand and thirdhand smoke)
Smokers have a 30% higher risk of developing dementia than non-smokers. They also put those around them at risk: Secondhand smoke contains 7,000 chemicals — and at least 70 of them can cause cancer.
Then there’s thirdhand smoke, which is not actually smoke. It’s the residue of cigarette smoke that creates the telltale smell on clothing or in a room. That residue alone can emit chemicals that are toxic to the brain.
6. Make social connections
In a recent study, people over the age of 55 who regularly participated in dinner parties or other social events had a lower risk of losing their memory. But it wasn’t because of what they ate, it was the effect of the repeated social connection.
To lessen isolation and loneliness, you can also boost brain chemicals like serotonin and endorphins by performing small acts of kindness:
- Wish others well or check in with somebody.
- Give a compliment without expecting anything in return.
- Make a phone call to somebody you don’t usually reach out to.
7. Continuously learn new skills
Maintaining a strong memory is not all about brain games like Sudoku, Wordle and crossword puzzles.
Learning skills and acquiring information are much more effective ways to make new connections in the brain. The more connections you make, the more likely you are to retain and even enhance your memory.
When you think about learning something new, approach it the way you would with fitness training. You want to work out different muscles on different days. The same goes for the brain.
Over the course of this week, try cross-training your brain by mixing mental activities (learning a new language or reading a book) and physical learning activities (playing tennis or soccer) .
By: Marc Milstein
Marc Milstein, PhD, is a brain health expert and author of “The Age-Proof Brain: New Strategies to Improve Memory, Protect Immunity, and Fight Off Dementia.” He earned both his PhD in Biological Chemistry and his Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA, and has conducted research on genetics, cancer biology and neuroscience. Follow him on Twitter and Instagram.
Source: A brain expert shares his 7 ‘hard rules’ for boosting memory and fighting off dementia
.
Related contents:
“Dementia”. medlineplus.gov. Retrieved 20 January 2022.Creavin ST, Wisniewski S, Noel-Storr AH, et al. (January 2016). “Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations” (PDF).
The Cochrane Database of Systematic Reviews. 2016 (1): CD011145. doi:10.1002/14651858.CD011145.pub2. hdl:1983/00876aeb-2061-43f5-b7e1-938c666030ab. PMC 8812342. PMID 26760674.“Differential diagnosis dementia”. NICE. Retrieved 20 January 2022.
Hales RE (2008). The American Psychiatric Publishing Textbook of Psychiatry. American Psychiatric Pub. p. 311. ISBN 978-1-58562-257-3. Archived from the original on 2017-09-08. Livingston G, Huntley J, Sommerlad A, et al. (August 2020). “Dementia prevention, intervention, and care: 2020 report of the Lancet Commission”. Lancet. 396 (10248): 413–446. doi:10.1016/S0140-6736(20)30367-6. PMC 7392084. PMID 32738937.
Nichols E, Szoeke CE, Vollset SE, Abbasi N, Abd-Allah F, Abdela J, et al. (GBD 2016 Dementia Collaborators) (January 2019). “Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016”. The Lancet. Neurology. 18 (1): 88–106. doi:10.1016/S1474-4422(18)30403-4. PMC 6291454. PMID 30497964.
Bathini P, Brai E, Auber LA (November 2019). “Olfactory dysfunction in the pathophysiological continuum of dementia” (PDF). Ageing Research Reviews. 55: 100956. doi:10.1016/j.arr.2019.100956. PMID 31479764. S2CID 201742825.
McKeith IG, Ferman TJ, Thomas AJ, et al. (April 2020). “Research criteria for the diagnosis of prodromal dementia with Lewy bodies”. Neurology (Review). 94 (17): 743–755. doi:10.1212/WNL.0000000000009323. PMC 7274845. PMID 32241955.
Budson A, Solomon P (2011). Memory loss : a practical guide for clinicians. [Edinburgh?]: Elsevier Saunders. ISBN 978-1-4160-3597-8.“ICD-11 for Mortality and Morbidity Statistics”. icd.who.int. Retrieved 20 January 2022.
Lin JS, O’Connor E, Rossom RC, Perdue LA, Eckstrom E (November 2013). “Screening for cognitive impairment in older adults: A systematic review for the U.S. Preventive Services Task Force”. Annals of Internal Medicine. 159 (9): 601–612. doi:10.7326/0003-4819-159-9-201311050-00730. PMID 24145578.
Ortega, V; Leung, P; Del-Pino-Casado, “Assessment and management of behavioral and psychological symptoms of dementia”. BMJ. 350: h369. doi:10.1136/bmj.h369. PMC 4707529. PMID 25731881.
Şahin Cankurtaran E (December 2014). “Management of Behavioral and Psychological Symptoms of Dementia”. Noro Psikiyatri Arsivi. 51 (4): 303–312. doi:10.5152/npa.2014.7405. PMC 5353163. PMID 28360647.“Inhibition in Cognition”. http://www.apa.org. Retrieved 7 February 2021.
Shub D, Kunik ME (April 16, 2009). “Psychiatric Comorbidity in Persons With Dementia: Assessment and Treatment Strategies”. Psychiatric Times. 26 (4). Archived from the original on April 27, 2009.“Dementia – Signs and Symptoms”. American Speech Language D Association.“Dementia: comorbidities in patients – data briefing”. GOV.UK. Retrieved 22 November 2020.
“Continence, dementia, and care that preserves dignity”. NIHR Evidence. 21 June 2022. doi:10.3310/nihrevidence_51255. S2CID 251785991. Grant RL, Drennan VM, Rait G, Petersen I, Iliffe S (August 2013). Prince MJ (ed.). “First diagnosis and management of incontinence in older people with and without dementia in primary care: a cohort study using The Health Improvement Network primary care database”. PLOS Medicine. 10 (8): e1001505. doi:10.1371/journal.pmed.1001505. PMC 3754889. PMID 24015113.
“What Is Dementia? | CDC”. http://www.cdc.gov. 2019-12-19. Retrieved 2022-10-03.Sheehan B (November 2012). “Assessment scales in dementia”. Ther Adv Neurol Disord. 5 (6): 349–358. doi:10.1177/1756285612455733. PMC 3487532. PMID 23139705.“Seven Stages of Dementia | Symptoms, Progression & Durations”. Retrieved 19 December 2020.
“Clinical Stages of Alzheimer’s”. Fisher Center for Alzheimer’s Research Foundation. 29 January 2014. Retrieved 19 December 2020.“Preclinical, Prodromal, and Dementia Stages of Alzheimer’s Disease”. Practical Neurology. trieved 2022-06-28.Bhatia-Dey N, Heinbockel T (June 2021).
“The Olfactory System as Marker of Neurodegeneration in Aging, Neurological and Neuropsychiatric Disorders”. Int J Environ Res Public Health. 18 (13): 6976. doi:10.3390/ijerph18136976. PMC 8297221. PMID 34209997.Boesveldt S, Parma V (January 2021). “The importance of the olfactory system in human well-being, through nutrition and social behavior”. Cell Tissue Res. 383 (1): 559–567. doi:10.1007/s00441-020-03367-7. PMC 7802608. PMID 33433688.
Sherman C, Liu CS, Herrmann N, Lanctôt KL (February 2018). “Prevalence, neurobiology, and treatments for apathy in prodromal dementia”. Int Psychogeriatr. 30 (2): 177–184. doi:10.1017/S1041610217000527. PMID 28416030. S2CID 46788701.Breton A, Casey D, Arnaoutoglou NA (February 2019). “Cognitive tests for the detection of mild cognitive impairment (MCI), the prodromal stage of dementia: Meta-analysis of diagnostic accuracy studies”. International Journal of Geriatric Psychiatry. 34 (2): 233–242. doi:10.1002/gps.5016. PMID 30370616. S2CID 53097138.
Bateman DR, Gill S, Hu S, Foster ED, Ruthirakuhan MT, Sellek AF, Mortby ME, Matušková V, Ng KP, Tarawneh RM, Freund-Levi Y, Kumar S, Gauthier S, Rosenberg PB, Ferreira de Oliveira F, Devanand DP, Ballard C, Ismail Z (2020). “Agitation and impulsivity in mid and late life as possible risk markers for incident dementia”.
Alzheimer’s & Dementia: Translational Research & Clinical Interventions. 6 (1): e12016. doi:10.1002/trc2.12016. PMC 7507499. PMID 32995467.Cervenka I, Agudelo LZ, Ruas JL (July 2017). “Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health”. Science. 357 (6349): eaaf9794. doi:10.1126/science.aaf9794. PMID 28751584.
Solvang SH, Nordrehaug JE, Aarsland D, et al. (2019). “Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia”. Int J Tryptophan Res. 12: 1178646919877883. doi:10.1177/1178646919877883. PMC 6769202. PMID 31632053.
Atri A (March 2019). “The Alzheimer’s Disease Clinical Spectrum: Diagnosis and Management”. Med Clin North Am. 103 (2): 263–293. doi:10.1016/j.mcna.2018.10.009. PMID 30704681. Hugo J, Ganguli M (August 2014). “Dementia and cognitive impairment: epidemiology, diagnosis, and treatment”.
Clinics in Geriatric Medicine. 30 (3): 421–442. doi:10.1016/j.cger.2014.04.001. PMC 4104432. PMID 25037289.American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders : DSM-5 (5th ed.). Washington, DC: American Psychiatric Association. pp. 591–603. ISBN 978-0-89042-554-1.Jenkins C, Ginesi L, Keenan B (2016). Dementia care at a glance. Chichester, West Sussex. ISBN 978-1-118-85998-8. OCLC 905089525.
Rohrer JD, Knight WD, Warren JE, Fox NC, Rossor MN, Warren JD (January 2008). “Word-finding difficulty: a clinical analysis of the progressive aphasias”. Brain. 131 (Pt 1): 8–38. doi:10.1093/brain/awm251. PMC 2373641. PMID 17947337.
Islam M, Mazumder M, Schwabe-Warf D, Stephan Y, Sutin AR, Terracciano A (February 2019). “Personality Changes With Dementia From the Informant Perspective: New Data and Meta-Analysis”. Journal of the American Medical Directors Association. 20 (2): 131–137. doi:10.1016/j.jamda.2018.11.004. PMC 6432780. PMID 30630729.
“Diagnosing Lewy Body Dementia”. National Institute on Aging. Retrieved 10 May 2020.Wilson RS, Sytsma J, Barnes LL, Boyle PA (September 2016). “Anosognosia in Dementia”. Current Neurology and Neuroscience Reports. 16 (9): 77. doi:10.1007/s11910-016-0684-z. PMID 27438597. S2CID 3331009.
Sunderaraman P, Cosentino S (March 2017). “Integrating the Constructs of Anosognosia and Metacognition: a Review of Recent Findings in Dementia”. Current Neurology and Neuroscience Reports. 17 (3): 27. doi:10.1007/s11910-017-0734-1. PMC 5650061. PMID 28283961.
Payne, M.; Morley, J. (1 May 2018). “Dysphagia, Dementia and Frailty”. The Journal of Nutrition, Health & Aging. 22 (5): 562–565. doi:10.1007/s12603-018-1033-5. PMID 29717753. S2CID 13753522.
Sala Della, S.; Spinnler, H.; Venneri, A. (2004). “Walking difficulties in patients with Alzheimer’s disease might originate from gait apraxia” (PDF). Journal of Neurology, Neurosurgery & Psychiatry. 75 (2): 196–201. Archived (PDF) from the original on 2022-10-09.Mc Ardle, Ríona; Galna, Brook; Donaghy, Paul; Thomas, Alan; Rochester, Lynn (20 September 2019).
“Do Alzheimer’s and Lewy body disease have discrete pathological signatures of gait?”. Alzheimer’s & Dementia. 15 (10): 1367–1377. doi:10.1016/j.jalz.2019.06.4953. PMID 31548122.“Mental, physical and speech abilities in later stages of dementia”. Alzheimer’s Society. 29 June 2022. etrieved 30 July 2022.Chung CG, Lee H, Lee SB (September 2018). “Mechanisms of protein toxicity in neurodegenerative diseases”. Cell Mol Life Sci. 75 (17): 3159–3180. doi:10.1007/s00018-018-2854-4. PMC 6063327. PMID 29947927.Wenk, Gary L. (2003).
“Neuropathologic changes in Alzheimer’s disease”. The Journal of Clinical Psychiatry. 64 (Suppl 9): 7–10. PMID 12934968.Iadecola C (November 2013). “The pathobiology of vascular dementia”. Neuron. 80 (4): 844–66. doi:10.1016/j.neuron.2013.10.008. PMC 3842016. PMID 24267647.“Vascular dementia – Symptoms and causes”. Mayo Clinic. Retrieved 2021-07-08.
McKeith IG, Ferman TJ, Thomas AJ, et al. (April 2020). “Research criteria for the diagnosis of prodromal dementia with Lewy bodies”. Neurology. 94 (17): 743–755. doi:10.1212/WNL.0000000000009323. PMC 7274845. PMID 32241955.McKeith IG, Boeve BF, Dickson DW, et al. (July 2017). “Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium”.
Neurology (Review). 89 (1): 88–100. doi:10.1212/WNL.0000000000004058. PMC 5496518. PMID 28592453.Taylor JP, McKeith IG, Burn DJ, et al. (February 2020). “New evidence on the management of Lewy body dementia”. Lancet Neurol (Review). 19 (2): 157–69. doi:10.1016/S1474-4422(19)30153-X. PMC 7017451. PMID 31519472. Courtesty link available here.
Gomperts SN (April 2016). “Lewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease Dementia”. Continuum (Minneap Minn) (Review). 22 (2 Dementia): 435–63. doi:10.1212/CON.0000000000000309. PMC 5390937. PMID 27042903.Finger EC (April 2016). “Frontotemporal Dementias”. Continuum. 22 (2 Dementia): 464–489. doi:10.1212/CON.0000000000000300. PMC 5390934. PMID 27042904.
“Progressive Supranuclear Palsy Fact Sheet | National Institute of Neurological Disorders and Stroke”. http://www.ninds.nih.gov. Retrieved 2021-01-20.Lopez G, Bayulkem K, Hallett M (October 2016). “Progressive supranuclear palsy (PSP): Richardson syndrome and other PSP variants”. Acta Neurol Scand. 134 (4): 242–9. doi:10.1111/ane.12546. PMC 7292631. PMID 27070344.Frank S (January 2014).
“Treatment of Huntington’s disease”. Neurotherapeutics. 11 (1): 153–60. doi:10.1007/s13311-013-0244-z. PMC 3899480. PMID 24366610.“Huntington’s disease – Symptoms”. nhs.uk. 2018-02-16. Retrieved 2022-06-28.“HIV-Associated Dementia – Neurologic Disorders”. MSD Manual Professional Edition.
Collinge J (July 2005). “Molecular neurology of prion disease”. Journal of Neurology, Neurosurgery, and Psychiatry. 76 (7): 906–919. doi:10.1136/jnnp.2004.048660. PMC 1739714. PMID 15965195.Ridley NJ, Draper B, Withall A (2013). “Alcohol-related dementia: an update of the evidence”. Alzheimers Res Ther. 5 (1): 3. doi:10.1186/alzrt157. PMC 3580328. PMID 23347747.
“What is mixed dementia?”. Alzheimer’s Society. Retrieved 2020-12-13.“Is dementia hereditary? | Alzheimer’s Society”. http://www.alzheimers.org.uk. Retrieved 2022-06-28.Schofield P (2005). “Dementia associated with toxic causes and autoimmune disease”. International Psychogeriatrics (Review). 17 (Suppl 1): S129–47. doi:10.1017/s1041610205001997. hdl:1959.13/24647. PMID 16240488. S2CID 11864913.Rosenbloom MH, Smith S, Akdal G, Geschwind MD (September 2009).
“Immunologically mediated dementias”. Current Neurology and Neuroscience Reports (Review). 9 (5): 359–67. doi:10.1007/s11910-009-0053-2. PMC 2832614. PMID 19664365.Zis P, Hadjivassiliou M (26 February 2019). “Treatment of Neurological Manifestations of Gluten Sensitivity and Coeliac Disease”. Curr Treat Options Neurol (Review). 21 (3): 10. doi:10.1007/s11940-019-0552-7. PMID 30806821.
“Attitudes and preferences towards screening for dementia: a systematic review of the literature”. BMC Geriatr. 15: 66. doi:10.1186/s12877-015-0064-6. PMC 4469007. PMID 26076729.“Dementia definition”. MDGuidelines. Reed Group. Archived from the original on 2009-06-29. Retrieved 2009-06-04. Gleason OC (March 2003). “Delirium”. American Family Physician. 67 (5): 1027–1034. PMID 12643363. Archived from the original on 2007-09-29.Lai CK (2014).
“The merits and problems of Neuropsychiatric Inventory as an assessment tool in people with dementia and other neurological disorders”. Clinical Interventions in Aging. 9: 1051–1061. doi:10.2147/CIA.S63504. PMC 4099101. PMID 25031530.Worrall L, Hickson LM (2003). “Implications for theory, practice, and policy”. In Worrall LE, Hickson LM (eds.). Communication disability in aging: from prevention to intervention. Clifton Park, NY: Delmar Learning. pp. 297–298. ISBN 978-0-7693-0015-3.James C, Ranson JM, Everson R, Llewellyn DJ (December 2021).
“Performance of Machine Learning Algorithms for Predicting Progression to Dementia in Memory Clinic Patients”. JAMA Network Open. 4 (12): e2136553. doi:10.1001/jamanetworkopen.2021.36553. PMC 8678688. PMID 34913981.Boustani M, Peterson B, Hanson L, Harris R, Lohr KN (June 2003). “Screening for dementia in primary care: a summary of the evidence for the U.S. Preventive Services Task Force”. Annals of Internal Medicine. 138 (11): 927–937. doi:10.7326/0003-4819-138-11-200306030-00015. PMID 12779304. S2CID 20779164.Cullen B, O’Neill B, Evans JJ, Coen RF, Lawlor BA (August 2007).
“A review of screening tests for cognitive impairment”. Journal of Neurology, Neurosurgery, and Psychiatry. 78 (8): 790–799. doi:10.1136/jnnp.2006.095414. PMC 2117747. PMID 17178826.Ranson JM, Kuźma E, Hamilton W, Muniz-Terrera G, Langa KM, Llewellyn DJ (April 2019). “Predictors of dementia misclassification when using brief cognitive assessments”. Neurology. Clinical Practice. 9 (2): 109–117. doi:10.1212/CPJ.0000000000000566. PMC 6461420. PMID 31041124.Sager MA, Hermann BP, La Rue A, Woodard JL (October 2006).
“Screening for dementia in community-based memory clinics” (PDF). WMJ. 105 (7): 25–29. PMID 17163083. Archived from the original (PDF) on 2010-06-26.“. Neurology. 68 (19): 1588–1595. doi:10.1212/01.wnl.0000258542.58725.4c. PMID 17287448. S2CID 9129604.Karlawish JH, Clark CM (March 2003). “Diagnostic evaluation of elderly patients with mild memory problems”. Annals of Internal Medicine. 138 (5): 411–419. doi:10.7326/0003-4819-138-5-200303040-00011. PMID 12614094. S2CID 43798118.
“Trail Making Test A and B: normative data stratified by age and education”. Archives of Clinical Neuropsychology. 19 (2): 203–214. doi:10.1016/S0887-6177(03)00039-8. PMID 15010086.“AD-8 for detection of dementia across a variety of healthcare settings”. The Cochrane Database of Systematic Reviews. 3: CD011121. doi:10.1002/14651858.CD011121.pub2. PMC 6398085. PMID 30828783.Bee P. “The five-minute test that can tell if you’re on the road to dementia”. Retrieved 1 January 2022.
“FDA Clears 5-Minute Test for Early Dementia”. Medscape. Retrieved 1 January 2022.Jorm AF (September 2004). “The Informant Questionnaire on cognitive decline in the elderly (IQCODE): a review”. International Psychogeriatrics. 16 (3): 275–293. doi:10.1017/S1041610204000390. PMID 15559753. S2CID 145256616.
.
Marketing Programs To Buy: