New research has reported a link between elevated blood levels of perfluooctane sulfate (PFOS) and increased risk of liver cancer. The study is the first to directly associate exposure from this “forever chemical” to liver cancer in humans.There are thousands of different chemicals under the umbrella of per- and polyfluoroalkyl substances, or PFAS. These substances are often informally referred to as “forever chemicals” because they can persist in the environment for decades.
For much of the 20th century PFAS chemicals were used in a broad variety of manufacturing contexts. However, over the past 20 years an increasing body of evidence has revealed exposure to PFAS can contribute to a number of deleterious health effects, from low birth weight to hypothyroidism.
Following on from animal and lab-based studies suggesting PFAS exposure is potentially damaging to liver cells, this new research offers the first robust investigation into the relationship between the chemicals and liver cancer in humans.
The power of this new research is in its leveraging of data from a multi-decade health study following more than 200,000 people since the early 1990s. This allowed the researchers to look at historic blood levels of PFAS in subjects years before they presented with cancer.“Part of the reason there has been few human studies is because you need the right samples,” explained Veronica Wendy Setiawan, an author on the new study. “When you are looking at an environmental exposure, you need samples from well before a diagnosis because it takes time for cancer to develop.”
Several types of PFAS were found in blood samples from subjects who ultimately went on to develop liver cancer. But one particular chemical stood out, perfluooctane sulfate (also known as PFOS). Those subjects with the highest blood levels of PFOS were 4.5 times more likely to develop liver cancer compared to the group with the lowest PFOS blood levels.
The study also homed in on some potential mechanisms by which PFOS exposure could be causing liver cancer. Four particular metabolites were found to link PFOS levels with liver cancer: “glucose, butyric acid (a short chain fatty acid), α-Ketoisovaleric acid (a branched-chain α-keto acid), and 7α-Hydroxy-3-oxo-4-cholestenoate (a bile acid).”
“We believe our work is providing important insights into the long-term health effects that these chemicals have on human health, especially with respect to how they can damage normal liver function,” explained lead researcher on the project Leda Chatzi. “This study fills an important gap in our understanding of the true consequences of exposure to these chemicals.”
The new findings come just days after another study found levels of PFAS in rainwater often exceed new safety limits set by the Environmental Protection Authority (EPA). That research called for a global phase-out of PFAS from all manufacturing contexts as soon as possible. An expert committee formed by the United Nations to review persistent pollutants in 2019 also called for the elimination of all use of PFAS chemicals to, “protect human health and the environment from its harmful impacts.”
Source: PFAS “forever chemicals” linked to liver cancer in first-of-its-kind study
Related contents:
Ex-PC lied about girlfriend’s cancer battle to get time off work
Ad of the Day: UV-sensitive poster helps public see the light on skin cancer
More Remote Working Apps:
https://givvy-numbers.app.link/qNDZMGGbhsb Givvy Mobile Lottery
https://quintexcapital.com/?ref=arminham Quintex Capital
https://www.genesis-mining.com/a/2535466 Genesis Mining
http://www.bevtraders.com/?ref=arminham BevTraders
https://www.litefinance.com/?uid=929237543 LiteTrading
https://cashbox.money/r/6ded936cbc264c7e9add5dd5565bb31a Cash Box Money
https://alpariforex.org/fa/registration/?cpa_partner_id=13687690 Alpari Forex Trading
https://dealcheck.io?fp_ref=armin16 Dealcheck Real Estate Evaluator
https://jvz8.com/c/202927/369164 prime stocks
https://jvz1.com/c/202927/373449 forrk
https://jvz3.com/c/202927/194909 keysearch
https://jvz4.com/c/202927/296191 gluten free
https://jvz1.com/c/202927/286851 diet fitness diabetes
https://jvz8.com/c/202927/213027 writing job
https://jvz6.com/c/202927/108695 postradamus
https://jvz1.com/c/202927/372094 stoodaio
https://jvz4.com/c/202927/358049 profile mate
https://jvz6.com/c/202927/279944 senuke
https://jvz8.com/c/202927/54245 asin
https://jvz8.com/c/202927/370227 appimize
https://jvz8.com/c/202927/376524 super backdrop
https://jvz6.com/c/202927/302715 audiencetoolkit
https://jvz1.com/c/202927/375487 4brandcommercial
https://jvz2.com/c/202927/375358 talkingfaces
https://jvz6.com/c/202927/375706 socifeed
https://jvz2.com/c/202927/184902 gaming jobs
https://jvz6.com/c/202927/88118 backlinkindexer
https://jvz1.com/c/202927/376361 powrsuite
https://jvz3.com/c/202927/370472 tubeserp
https://jvz4.com/c/202927/343405 PR Rage
https://jvz6.com/c/202927/371547 design beast
https://jvz3.com/c/202927/376879 commission smasher
https://jvz2.com/c/202927/376925 MT4Code System
https://jvz6.com/c/202927/375959 viral dash
https://jvz1.com/c/202927/376527 coursova
https://jvz4.com/c/202927/144349 fanpage
https://jvz1.com/c/202927/376877 forex expert
https://jvz6.com/c/202927/374258 appointomatic
https://jvz2.com/c/202927/377003 woocommerce
https://jvz6.com/c/202927/377005 domainname
https://jvz8.com/c/202927/376842 maxslides
https://jvz8.com/c/202927/376381 ada leadz
https://jvz2.com/c/202927/333637 eyeslick
https://jvz1.com/c/202927/376986 creaitecontentcreator
https://jvz4.com/c/202927/376095 vidcentric
https://jvz1.com/c/202927/374965 studioninja
https://jvz6.com/c/202927/374934 marketingblocks
https://jvz3.com/c/202927/372682 clipsreel
https://jvz2.com/c/202927/372916 VideoEnginePro
https://jvz1.com/c/202927/144577 BarclaysForexExpert
https://jvz8.com/c/202927/370806 Clientfinda
https://jvz3.com/c/202927/375550 Talkingfaces
https://jvz1.com/c/202927/370769 IMSyndicator
https://jvz6.com/c/202927/283867 SqribbleEbook
https://jvz8.com/c/202927/376524 superbackdrop
https://jvz8.com/c/202927/376849 VirtualReel
https://jvz2.com/c/202927/369837 MarketPresso
https://jvz1.com/c/202927/342854 voiceBuddy
https://jvz6.com/c/202927/377211 tubeTargeter
https://jvz6.com/c/202927/377557 InstantWebsiteBundle
https://jvz6.com/c/202927/368736 soronity
https://jvz2.com/c/202927/337292 DFY Suite 3.0 Agency+ information
https://jvz8.com/c/202927/291061 VideoRobot Enterprise
https://jvz8.com/c/202927/327447 Klippyo Kreators
https://jvz8.com/c/202927/324615 ChatterPal Commercial
https://jvz8.com/c/202927/299907 WP GDPR Fix Elite Unltd Sites
https://jvz8.com/c/202927/328172 EngagerMate
https://jvz3.com/c/202927/342585 VidSnatcher Commercial
https://jvz3.com/c/202927/292919 myMailIt
https://jvz3.com/c/202927/320972 Storymate Luxury Edition
https://jvz2.com/c/202927/320466 iTraffic X – Platinum Edition
https://jvz2.com/c/202927/330783 Content Gorilla One-time
https://jvz2.com/c/202927/301402 Push Button Traffic 3.0 – Brand New
https://jvz2.com/c/202927/321987 SociCake Commercial
https://jvz2.com/c/202927/289944 The Internet Marketing
https://jvz2.com/c/202927/297271 Designa Suite License
https://jvz2.com/c/202927/310335 XFUNNELS FE Commercial
https://jvz2.com/c/202927/291955 ShopABot
https://jvz2.com/c/202927/312692 Inboxr
https://jvz2.com/c/202927/343635 MediaCloudPro 2.0 – Agency
https://jvz2.com/c/202927/353558 MyTrafficJacker 2.0 Pro+
https://jvz2.com/c/202927/365061 AIWA Commercial
https://jvz2.com/c/202927/357201 Toon Video Maker Premium
https://jvz2.com/c/202927/351754 Steven Alvey’s Signature Series
https://jvz2.com/c/202927/344541 Fade To Black
https://jvz2.com/c/202927/290487 Adsense Machine
https://jvz2.com/c/202927/315596 Diddly Pay’s DLCM DFY Club
https://jvz2.com/c/202927/355249 CourseReel Professional
https://jvz2.com/c/202927/309649 SociJam System
https://jvz2.com/c/202927/263380 360Apps Certification
https://jvz2.com/c/202927/359468 LocalAgencyBox
https://jvz2.com/c/202927/377557 Instant Website Bundle
https://jvz2.com/c/202927/377194 GMB Magic Content
https://jvz2.com/c/202927/376962 PlayerNeos VR
https://jvz8.com/c/202927/381812/ BrandElevate Bundle information
https://jvz4.com/c/202927/381807/ BrandElevate Ultimate
https://jvz2.com/c/202927/381556/ WowBackgraounds Plus
https://jvz4.com/c/202927/381689/ Your3DPal Ultimate
https://jvz2.com/c/202927/380877/ BigAudio Club Fast Pass
https://jvz3.com/c/202927/379998/ Podcast Masterclass
https://jvz3.com/c/202927/366537/ VideoGameSuite Exclusive
https://jvz8.com/c/202927/381148/ AffiliateMatic
https://jvzoo.com/c/202927/381179 YTSuite Advanced
https://jvz1.com/c/202927/381749/ Xinemax 2.0 Commercial
https://jvzoo.com/c/202927/382455 Living An Intentional Life
https://jvzoo.com/c/202927/381812 BrandElevate Bundle
https://jvzoo.com/c/202927/381935 Ezy MultiStores
https://jvz2.com/c/202927/381194/ DFY Suite 4.0 Agency
https://jvzoo.com/c/202927/381761 ReVideo
https://jvz4.com/c/202927/381976/ AppOwls Bundle
https://jvz8.com/c/202927/381950/ TrafficForU
https://jvz3.com/c/202927/381615/ WOW Backgrounds 2.0
https://jvz4.com/c/202927/381560 ALL-in-One HD Stock Bundle
https://jvz6.com/c/202927/382326/ Viddeyo Bundle
https://jvz8.com/c/202927/381617/ The Forex Joustar
https://jvz3.com/c/202927/383751/ ADA Web Accessibility Compliance
https://jvz3.com/c/202927/383942/ 10 Bold Actions In Positive Life & Work
https://jvz3.com/c/202927/383706/ Adtivate Agency
https://jvz1.com/c/202927/384099/ My Passive Income Blueprints
https://jvz3.com/c/202927/329145/ Content Tool Kit
https://jvz6.com/c/202927/382663/ ReviewReel
https://jvz3.com/c/202927/383865/ QR Verse Bundle
https://jvz4.com/c/202927/379307/ VIADZ Ad Template
https://jvz2.com/c/202927/383051/ EngageYard Ad Creator
https://jvz4.com/c/202927/381011/ Videevolve
https://jvz4.com/c/202927/383751/ Local Leader Bundle
https://jvz8.com/c/202927/383119/ Tonai Voice Content
https://jvz2.com/c/202927/383848/ Vocalic Commercial
https://jvz3.com/c/202927/383483/ Dropshiply Store Creator
https://jvz6.com/c/202927/384025/ Levidio Royal Podcasting
https://jvz6.com/c/202927/383094/ Develop Self Empowerment
https://jvz1.com/c/202927/379223/ Hostley Domain Creator
https://jvz6.com/c/202927/383447/ Mech Forex Robot
https://jvz4.com/c/202927/383177/ Motion Kingdom Studio
https://jvz8.com/c/202927/144577/ Forex Blizz Trading
https://jvz3.com/c/202927/382851/ AdRaven
https://jvz2.com/c/202927/383307/ Animaxime V2
https://jvz8.com/c/202927/375692/ Promovidz Promotion Videos
https://jvz3.com/c/202927/381148/ AffiliateMatic
https://jvz4.com/c/202927/379051/ CanvaKitz Business Templates
https://jvz1.com/c/202927/383113/ Agencyscale Business Agency
https://jvz3.com/c/202927/347847/ Pitchdeck Professional Presentations
https://jvz2.com/c/202927/381179/ YTSuite YouTube Ads Campaigns
https://jvz8.com/c/202927/382455/ Living an International Life
https://jvz1.com/c/202927/188236/ Galactic Dimension backgrounds
https://jvz6.com/c/202927/381749/ Xinemax Hollywood Creator
https://jvz3.com/c/202927/381194/ DFY Suite 4.0 Agency
https://jvz4.com/c/202927/381231/ Appowls Mobile Apps
https://jvz1.com/c/202927/381935/ Ezy Multi Stores
https://jvz3.com/c/202927/381950/ TrafficForU
https://jvz2.com/c/202927/381556/ WOW Backgrounds
https://jvz2.com/c/202927/381685/ Your 3DPal
https://jvz6.com/c/202927/381617/ Forex Joustar
https://jvz2.com/c/202927/381129/ Ultrafunnels A.I
https://jvz3.com/c/202927/128215/ DUX Forex Signals
https://jvz3.com/c/202927/381003/ Trendio Keyword Content
https://jvz1.com/c/202927/381439/ FX Goldminer
https://jvz2.com/c/202927/380937/ Linkomatic
https://jvz2.com/c/202927/378775/ Pixal 2.022
https://jvz1.com/c/202927/379983/ VidVoicer
https://jvz6.com/c/202927/380087/ Big Audio Club
https://jvz1.com/c/202927/379995/ Podcast Advantage
https://jvz8.com/c/202927/380159/ Reputor
https://jvz6.com/c/202927/379863/ TubePal
https://jvz4.com/c/202927/380543/ Local Sites
https://jvz1.com/c/202927/369500/ PodKastr Commercial
https://jvz6.com/c/202927/351606/ Insta Keyword
https://jvz1.com/c/202927/376325/ Facedrip
https://jvz8.com/c/202927/374505/ 7 Minutes Kit
https://jvz6.com/c/202927/383057/ Aweber Crash Course
https://jvz3.com/c/202927/46987/ WP Simulator
https://jvz8.com/c/202927/379995/ Podcast Advantage
https://jvz2.com/c/202927/380692/ Boost Optimism
https://jvz1.com/c/202927/36517/ PlanB Muscle Growth
https://jvz6.com/c/202927/379480/ TV Boss Fire
https://jvz1.com/c/202927/379455/ Webprimo Website Builder
https://jvz2.com/c/202927/379339/ LocalCentric
https://jvz4.com/c/202927/378683/ WebCop
https://jvz3.com/c/202927/384619/ Agency Client Finder
https://jvz8.com/c/202927/384625/ Power Reviews
https://jvz8.com/c/202927/380933/ Survai
https://jvz2.com/c/202927/378775/ Pixal
https://jvz3.com/c/202927/383937/ Webinarkit
https://jvz2.com/c/202927/384700/ YoDrive
https://jvz4.com/c/202927/353373/ Rewriter
https://jvz1.com/c/202927/384630/ Appoint B Agency
https://jvz1.com/c/202927/267113/ Sunday Freebie
https://jvz2.com/c/202927/384573/ EBook Agency
https://jvz2.com/c/202927/75989/ Ejaculation Total
https://jvz3.com/c/202927/359081/ Quit Smoking
https://jvz2.com/c/202927/353694/ Mobi First
https://jvz3.com/c/202927/378143/ Syndranker
https://jvz6.com/c/202927/378359/ VidMingo
https://jvz6.com/c/202927/384848/ Heal Your Emptiness
https://jvz6.com/c/202927/384381/ RSI SEO
https://jvz4.com/c/202927/382333/ Facebook Cash Machin
https://jvz3.com/c/202927/184902/ Video Games
https://jvz2.com/c/202927/383555/ KoinCart
https://jvz2.com/c/202927/358870/ Diabetes Guide
https://jvz4.com/c/202927/353334/ Fitness Nutrition Guide
https://jvz8.com/c/202927/366872/ Organic Life Guide
https://jvz8.com/c/202927/367353/ Human Synthesys Studio
https://jvz8.com/c/202927/384653/ 9 figure Success
https://jvz8.com/c/202927/383809/ Crypto Kit
https://jvz2.com/c/202927/366972/ AdzHero
https://jvz1.com/c/202927/385046/ Stackable Picture
https://jvz8.com/c/202927/25069/ Forex Atlatian
https://jvz6.com/c/202927/132677/ Forex Scouts
https://jvz6.com/c/202927/378113/ Crypto Rocket
https://jvz4.com/c/202927/377665/ PigMoney Method
https://jvz8.com/c/202927/374345/ Crypto Underworld
https://jvz3.com/c/202927/372305/ XBrain Forex