A Quick Guide to Developing Recipes

One of the most important aspects of professional cooking is developing recipes. A well-developed recipe achieves balance and consistency.

In this quick guide, we will discuss the steps chefs follow in developing recipes, and how meez has enhanced the recipe development process.

Inspiration and Ideation

Chefs can be inspired by art, seasonality, architecture, makers, ingredients or a story we want to tell. Professional chefs are as inspired by dishes at restaurants and meals our grandmothers used to make like anyone who cooks.

Once we have an idea, we think about the ingredients and flavors that will go into the recipe. We consider any restrictions or preferences that our diners or intended audience may have, including budget. Then we work with those guidelines.

Research and Visualization

Researching can entail visiting a farmers market, tasting the same ingredient from different purveyors, traveling, experiencing cultural influences and studying topics. We often consider sustainability, locality and if the businesses we work with align with our standards and goals. We consider making substitutions for ingredients that aren’t available or that are too expensive.

We visualize what the dish will look like and play with texture, shapes, colors and plates.

With meez, we can export an order list to source ingredients and keep notes and sketches in our Docs. We can even keep a R&D concept separate from production concepts to save each version of a dish until it makes a menu.

Drafting a Dish

We record the ingredients and instructions for a recipe in meez as we go. It’s important to be as specific as possible when writing a recipe so that anyone who reads it will be able to successfully replicate the dish. You can drag and drop a photo or video into each prep step to make this easier and to look back as you compare test versions.

Recipe Testing

We document everything we do when testing a recipe: ingredient amounts, temperatures, times, techniques. We evaluate salt, sweetness, spice, acid, fat, texture, umami and more to achieve balance and play with portion sizes, flavor combinations, elements and components.

Taste Testing

We often test with the back of house team to collaborate on feedback, ideas and iterations. Chefs might try a dish as a special for diner feedback as well. The tasting notes can be recorded in Docs as a menu is developed.

Recipe Writing

It’s crucial in a professional culinary setting to record clear and concise recipes as they’re developed, iterated and executed. With meez, you can convert units of measurement, scale, cost and see nutrition information as you build the recipe. It’s important that anyone who comes into work can replicate the recipe with all the content saved in meez, from the prep to photos and videos for plating. We often organize in recipe books based on station, season or section of the menu.

Once the recipe is developed, the chef can share view access with the team, copies with friends and colleagues, and a public link on social media when desired.

Source: A Quick Guide to Developing Recipes | Blog | meez

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The 5 Most Commonly Reported Covid-19 Symptoms

 

The official list of Covid-19 symptoms should be expanded as the existing one could “miss many Covid-19 cases”, experts have argued. The UK should follow other countries and include a broader range of symptoms, according to a group of scientists. Classic symptoms of Covid-19, listed on the NHS website, are a high temperature, a new continuous cough and/or a loss or change to a person’s sense of smell or taste.

But the most commonly reported symptoms by people taking part in the Office for National Statistics (ONS) Covid-19 Infection Survey are cough, headache and fatigue. The latest ONS release shows 61% of people who tested positive reported symptoms. Of these, 42% had a cough, 39% reported headache and 38% reported fatigue, according to the ONS.

Muscle ache was reported by a quarter of people and 32% reported having a sore throat. Meanwhile a third reported fever and 21% reported loss of smell and 15% reported loss of taste. A separate study – the Zoe Covid Symptom study – recently reported that a headache, sore throat and runny nose are now the most commonly reported symptoms. These are most likely symptoms of the Delta variant.

Writing in the British Medical Journal (BMJ), Dr Alex Crozier and colleagues – including Professor Calum Semple who is a member of Sage – suggest that limiting testing to only people with fever, cough and a change in taste or smell could “miss or delay identification of many Covid cases”.

They suggest this could “hamper efforts to interrupt transmission” of the virus. The group argue that increasing the symptom list could improve Britain’s pandemic response by expanding the criteria for self-isolation and eligibility for symptomatic testing.

The “narrow” case definition “limits” the early detection of contagious people, which restricts the efforts of the Test and Trace programme, they say. Non-traditional symptoms “often manifest earlier”, they added. The US Centres for Disease Control lists 11 more symptoms than the UK, and the World Health Organisation includes nine more. The testing capabilities are now able to facilitate people with a broader spectrum of symptoms, they added.

They say testing people with a single non-specific symptom could overwhelm capacity in the UK, but “combinations of symptoms could be used to help identify more cases sooner without overwhelming testing capacity”. The authors continue: “The UK’s decision to adopt a narrow case definition was based on ease of communication, avoiding confusion with other infections and preserving testing capacity.

People who had mild symptoms at first can still have long-term problems, says the NHS. The signs of long Covid vary from person to person, but the NHS now lists the following common symptoms: extreme tiredness (fatigue), shortness of breath , chest pain or tightness , problems with memory and concentration (“brain fog”), difficulty sleeping (insomnia), heart palpitations, dizziness , pins and needles ,joint pain, depression and anxiety, tinnitus, earaches, feeling sick, diarrhoea, stomach aches, loss of appetite, a high temperature, cough, headaches, sore throat, changes to sense of smell or taste and rashes.

This situation is now different — testing capacity is high. “Covid-19 is associated with a wide range of symptoms. Many patients do not experience the UK’s official case-defining symptoms, initially, or ever, and other symptoms often manifest earlier. Limiting the symptomatic testing to those with these official symptoms will miss or delay identification of many Covid-19 cases, hampering efforts to interrupt transmission.

“Expanding the clinical case definition of Covid−19, the criteria for self-isolation, and eligibility for symptomatic testing could improve the UK’s pandemic response. The Department of Health and Social Care has been approached for comment by PA Media. We will update this piece if there is a response.

The reason women might be more susceptible to long Covid might lie in differences in how our immune systems work – or that’s what scientists hypothesise, anyway. Research is needed to look into this. In a 2016 review on the differences in immune responses between males and females, professor Sabra Klein, of The Johns Hopkins Bloomberg School of Public Health, and professor Katie Flanagan, of Monash University, said females’ strong immune responses result in faster clearance of pathogens and greater vaccine efficacy compared to males. But it also contributes to females’ increased susceptibility to inflammatory and autoimmune diseases.

By:

Source: The 5 Most Commonly Reported Covid-19 Symptoms | HuffPost UK Life

.

Critics:

Patients with COVID-19 can present with neurological symptoms that can be broadly divided into central nervous system involvement, such as headache, dizziness, altered mental state, and disorientation, and peripheral nervous system involvement, such as anosmia and dysgeusia. Some patients experience cognitive dysfunction called “COVID fog“, or “COVID brain fog”, involving memory loss, inattention, poor concentration or disorientation. Other neurologic manifestations include seizures, strokes, encephalitis, and Guillain–Barré syndrome (which includes loss of motor functions).

Other neurological symptoms appear to be rare, but may affect half of patients who are hospitalized with severe COVID-19. Some reported symptoms include delirium, stroke, brain hemorrhage, memory loss, psychosis, peripheral nerve damage, anxiety, and post-traumatic stress disorder.

Neurological symptoms in many cases are correlated with damage to the brain’s blood supply or encephalitis, which can progress in some cases to acute disseminated encephalomyelitis. Strokes have been reported in younger people without conventional risk factors.

As of September 2020, it was unclear whether these symptoms were due to direct infection of brain cells, or of overstimulation of the immune system. A June 2020 systematic review reported a 6–16% prevalence of vertigo or dizziness, 7–15% for confusion, and 0–2% for ataxia.

References

5 Key Variables That Will Impact Our Return To “Normal”

An illustration of a needle and rode - The road back to normalcy

As vaccines roll out around the world, the question on everybody’s mind, is what does the journey back to “normal” look like? A new normal won’t return at the flip of a switch. We need to understand what’s happening, and we need trusted data to do that. So what should we be tracking? What metrics do we need to make effective, data-driven decisions? And, how do we know if we’re on the path to normalcy?

We recently spoke with Dr. Sam Scarpino, complex systems scientist, and assistant professor at the Network Science Institute at Northeastern University. With his help, we’ve identified five key variables that can help us measure our progress to a state resembling normalcy. In other words, when data will tell us when and how we can return to a simpler—if not quite normal—life.

1. Vaccine effectiveness

The first variable is, of course, the vaccines themselves. In our conversation, Scarpino shared two important variables regarding vaccine rollout:

  1. Transmission: The amount that vaccines reduce transmission
  2. Deployment: How quickly we can roll out vaccines across the country and internationally

Public and private healthcare organizations will need to track these data at a granular level.

Scarpino also emphasized the need for passive, always-on surveillance for COVID-19 and for genomic variants, like the B.1.1.7 variant in the United Kingdom. “Without these surveillance systems, we’re going to be continually caught off-guard by this disease and the “new normal” will feel a lot less normal,” said Scarpino.

2. Vaccine distribution

Next, we have to consider the huge task of distributing and administering the vaccines. This of course brings production and logistical challenges from mass shipping of perishable products, to scaling delivery to patients within myriad healthcare systems. And most critical of all, prioritizing what groups should be vaccinated first, and managing follow-up to ensure second doses are administered on schedule.

“At this stage, the biggest obstacle is delivery of the vaccines,” shared Scarpino. “Given the lack of a uniform national plan, states and localities are creating their own distribution and vaccination plans. Every state has a different approach, with varying levels of success. As a result, we’re already seeing dreadfully slow uptake. What this means is that we need more federal support for community health organizations administering the vaccine and public health agencies monitoring and coordinating our responses.”

There are also concerns around equal access to vaccinations.

Communities of color and Native American populations have experienced an increased burden of COVID-19, as a direct result of generations of systemic racism that have impacted health and access to healthcare. As a country, and internationally, we need to engage with individuals in these communities to ensure they have a voice and vote in how vaccines are prioritized.”

3. Vaccine acceptance and uptake

The third key variable is vaccine acceptance and uptake, which is difficult to predict. Vaccine acceptance is about building trust within local communities, especially where vaccine hesitancy is the norm. Uptake, on the other hand, is about vaccinations itself. Is it fast, easy, and accessible? The story of COVID-19 is fundamentally a local story, so what we really need are data insights at the postal code level.

“The first step is a critical and realistic assessment of our failures and successes, which requires data,” shared Scarpino. “If we don’t have detailed enough data around uptake, we can’t see which communities are close to herd-immunity and which are further away. We’ll be in the dark trying to respond to COVID-19 flare-ups.”

4. Testing speed and availability

It’s going to take time to roll out the vaccine. But with focus shifting to the vaccine itself, we can’t forget the importance of testing. We need to address questions like:

  • How available is on-demand testing?
  • What are the barriers that prevent people from being tested?
  • How long do the results take? Hours or days?

With this data, communities can identify hot spots and businesses gain insights they need to reopen, getting us one step closer to normalcy.

Scarpino emphasized that “high-rates of testing, paired with isolation, quarantine, and contact tracing can control COVID-19 even without a vaccine,” based on models and data from countries like Vietnam and Australia. “With the proper non-pharmaceutical interventions, we could potentially reach normalcy in months instead of years,” shared Scarpino.

5. Contact tracing

Finally, even with testing, vaccines, and wide scale public health measures, nothing beats good old fashioned contact tracing.

“Contact tracing—and its vital partner, case investigation to determine the source of infections—remains our best tool for fighting this disease,” shared Scarpino.

Closely monitoring where, when, and by whom one was exposed will help people understand if they are at risk, and take the right precautions, especially if they are asymptomatic. Contact tracing is foundational to the path to normalcy, by making sure that exposed individuals are aware, they can take actions to limit further transmission.

“We’ve seen myriad countries, like Japan, Thailand, Vietnam, Mongolia, China, South Korea, Taiwan, New Zealand, Australia, to name only a few, control this disease with testing, tracing, and isolation,” said Scarpino.

The vaccine also requires multiple doses, so Scarpino noted that “we need effective, and accurate systems, for monitoring uptake and ensuring individuals receive all the necessary rounds of inoculation. If our contact tracing systems aren’t working, we can’t control the disease and we can’t ensure individuals are being vaccinated properly.”

Getting back to “normal” takes all of us

Over the next few months, these factors will drive how quickly or how well things will return to normal for citizens, communities, and the economy.

“What we’ve seen over the past year is that society’s deepest challenges—from racism and its lasting effects, to chronically underfunding public health, or access to affordable healthcare and housing—largely dictated the course of this pandemic,” shared Scarpino.

“We can build a brighter, safer, and more productive future. One that will help us return to normal faster and prevent this from happening again. But it’s going to take all of us, working together and it has to start now.”

For more information, check out the Tableau COVID-19 Data Hub, where you can explore dashboards, find actionable insights, and visualize your own analyses.

From connection through collaboration, Tableau is the most powerful, secure, and flexible end-to-end analytics platform for your data. Elevate people with the power of data. Designed for the individual, but scaled for the enterprise, Tableau is the only business intelligence platform that turns your data into insights that drive action

Source: 5 Key Variables That Will Impact Our Return To “Normal”

.

References

Nigerian Filmmaker, Teniola Olatoni Premieres “The New Normal” to Rave Reviews, AP, November 18, 2020

Ford Doubling Investment In Electric Cars And Trucks To $22 Billion

Ford released its fourth quarter 2020 financial results Thursday after the markets closed and posted a net loss for the quarter of $2.8 billion and $1.3 billion for the full year. None of that was surprising. However, Ford also announced a doubling of its investment in electrified vehicles to $22 billion through 2025 and an increase in its total investment in automated driving to $7 billion from $4 billion.

Ford began delivering the Mustang Mach-E, its first purpose-built electric vehicle, in late December and plans to ramp up deliveries beginning this month. Mach-Es for North America and Europe are being produced in Mexico, but the automaker recently announced it would add production for the Chinese market from its Changan assembly plant this spring.

So far, Ford has announced three new battery electric vehicles, the Mach-E, the e-Transit commercial van coming this fall and an electric F-150 due out in 2022.

“We are accelerating all our plans – breaking constraints, increasing battery capacity, improving costs and getting more electric vehicles into our product cycle plan,” Jim Farley, Ford CEO said.

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As part of the expanded commitment, Ford says that electric vehicles will be fundamental to the premium Lincoln brand. Similar strategies are being followed by many other automakers including General Motors GM +0.5% GM +0.5% GM +0.5% GM +0.5% which is targeting 2030 to have all Cadillacs be electric.

Ford hasn’t revealed any other specific electric products yet, but as part of its latest contract with the Canadian UNIFOR union, it did commit to building electric vehicles at the Oakville, Ontario assembly plant. In addition to Oakville, Cuautitlán, Mexico is building the Mach-E, Dearborn, Mich will produce the F-150 and the Kansas City assembly plant will build the e-Transit. MORE FOR YOU

Elon Musk’s Ex-Chief Engineer Creates A New Car—And Says It Beats TeslaID.6 EV SUV Details Not Leaked By China, Volkswagen AdmitsDidi Makes $1 Billion Profit While Uber Bleeds — Good News For Robotaxis

In support of growing EV sales, Ford is also expanding the charging network available through the Fordpass app from 13,500 to 16,000. Ford EV owners can set up payment through the app and then automatically get billed at chargers that are part of the network when the vehicle is plugged in.

As part of the ongoing development of its automated vehicle program, the Argo AI fleet in Miami undertook a charitable goods pilot delivery program during the fourth quarter. Vehicles completed address-to-address autonomous deliveries of groceries and school supplies. Ford and Argo AI are now testing fourth-generation prototypes based on the Ford Escape Hybrid which feature the production intent hardware configuration prior to the planned commercial launch of services in 2022. Those services are expected to debut in Miami, Washington DC and Austin, Texas.

Follow me on Twitter or LinkedIn. Check out my website.

Sam Abuelsamid

 Sam Abuelsamid

I’ve spent my adult life working in and around the automotive industry. After earning a mechanical engineering degree from GMI I spent the next 17 years working on electronic control systems that help cars stop, go and change direction before I drove away to write about what other engineers were creating. Since then I’ve been trying to educate my readers, viewers and listeners about how the latest automotive technology works, what it can do and perhaps more importantly, what it can’t do. Since 2014 I’ve been combining my communications and engineering knowledge as a principal analyst with Navigant Research covering alternative fuels, advanced driving technologies and connected vehicles. I also co-host the Wheel Bearings podcast at https://wheelbearings.media/

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National security and government regulations on tech

This College Professor Became An Overnight Billionaire Fighting Covid

Every time you’re infected by bacteria or a virus, your immune system works to create treatments to defeat it. Molecularly unique to each person, these tiny cells, or antibodies, either destroy these invaders or mark them for other killer cells to track down.

Carl Hansen, 46, is geeking out as he describes the process over Zoom. “We can make 100 trillion different antibodies,” he exclaims. “The immune system is spectacular beyond description.”

If that sounds more like a college professor than the CEO of a $13 billion (market cap) biotech company, there’s a reason: Hansen was one—until 2019, when he left to focus on Vancouver-based AbCellera Biologics, cofounded with fellow researchers from the University of British Columbia in 2012. “Universities are very good at testing new ideas and looking for which road might be effective,” he says.

The team’s academic bent has played out in an even more important way. Nearly all biotech startups develop a handful of treatment targets, then spend the next 8 to 12 years developing those drugs, hoping to bring at least one of them to market. It’s not a sure thing—fewer than 10% of new drugs make it all the way. But when they do, they tend to be blockbusters: Seven of the ten top-selling drugs in 2018 were antibody treatments, including AbbVie’s $19 billion (net revenue) immunosuppressive drug Humira and Merck’s cancer drug Keytruda, which generated $11.1 billion in 2019.

AbCellera takes a vastly different approach. Instead of trying to build a vertically integrated drug company, it is focused solely on the discovery process. That’s the portion of drug development that is earliest and most essential: It’s there that the most promising treatment prospects are selected, subjected to early laboratory tests and then moved through the pipeline.

But AbCellera, which raised $105 million from investors including Peter Thiel, the University of Minnesota and OrbiMed in May—at a valuation of $4.8 billion, according to PitchBook, just six months before going public—is not interested in seeing it through from beginning to end. Instead it offers what might be described as “drug discovery as a service.” It works with 90 outside businesses, including pharma giants Pfizer, Gilead and Novartis. Those companies ask the biotech to find antibodies that meet certain criteria. AbCellera then uses its proprietary technology to find prospects.

In its highest-profile success to date, AbCellera examined thousands of antibodies derived from the blood of people who had recovered from Covid-19 in order to identify the antibodies that did the best job fighting the virus. It then turned over the most promising antibodies to drug company Eli Lilly. Clinical trials of one of those antibodies, bamlanivimab, began in May—just 90 days after the partnership started. Tests found patients with mild or moderate cases had good results, and in November, the antibody received emergency-use authorization from the FDA.

The federal government has contracted to purchase 950,000 doses of the drug for $1.2 billion. Eli Lilly issued guidance in mid-December expecting up to $2 billion in revenue from Covid-19 therapeutics in 2021, the bulk of which will come from bamlanivimab; AbCellera, which booked $25 million through the end of September 2020, will earn estimated royalties of $270 million on those sales, according to Credit Suisse.

AbCellera is also looking to speed up the time it takes to develop its antibody therapies. The shorter time frame saves millions in development costs while enabling revenues to come in sooner than expected. “From a financial perspective, every year that you save is a huge opportunity cost for investors,” says Gal Munda, an analyst at Berenberg Capital Markets.

Hansen is now worth $3 billion, thanks to the company’s white-hot December IPO. Asked about his meteoric rise into the three-comma club, Hansen is low-key: “It feels just a little bit surreal.” He’s more articulate about the biotech’s success: “If this example of Covid shows one thing, to me, it’s the proof point of the business model and the technology.”Follow me on Twitter or LinkedIn. Check out my website. Send me a secure tip

Alex Knapp

Alex Knapp

I’m a senior editor at Forbes covering healthcare, science, and cutting edge technology. 

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AbCellera Biologics CEO Carl Hansen joins ‘Closing Bell’ to discuss the company’s partnership with Eli Lilly in developing monoclonal antibody treatment and the company’s Covid-19 treatments. For access to live and exclusive video from CNBC subscribe to CNBC PRO: https://cnb.cx/2NGeIvi​ » Subscribe to CNBC TV: https://cnb.cx/SubscribeCNBCtelevision​ » Subscribe to CNBC: https://cnb.cx/SubscribeCNBC​ » Subscribe to CNBC Classic: https://cnb.cx/SubscribeCNBCclassic​ Turn to CNBC TV for the latest stock market news and analysis. From market futures to live price updates CNBC is the leader in business news worldwide. The News with Shepard Smith is CNBC’s daily news podcast providing deep, non-partisan coverage and perspective on the day’s most important stories. Available to listen by 8:30pm ET / 5:30pm PT daily beginning September 30: https://www.cnbc.com/2020/09/29/the-n…​ Connect with CNBC News Online Get the latest news: http://www.cnbc.com/​ Follow CNBC on LinkedIn: https://cnb.cx/LinkedInCNBC​ Follow CNBC News on Facebook: https://cnb.cx/LikeCNBC​ Follow CNBC News on Twitter: https://cnb.cx/FollowCNBC​ Follow CNBC News on Instagram: https://cnb.cx/InstagramCNBChttps://www.cnbc.com/select/best-cred..

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